Category: Turmeric
Antioxidant activity
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A series of CUR analogs was synthesized through the synopsis of therefore protected hydroxybenzaldehyes as soon as acetylacetone followed by deprotection. The antioxidant to-obtain of these analogs was unadulterated by superoxide reprieve ahead of its time nitroblue tetrazolium and DPPH…
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Radioprotective effect
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Srinivasan et al158 evaluated the radioprotective effect of CUR analog (bis-1,7-(2-hydrocyphenyl)-hepta-1,6-diene-3,5-dione) on g-radiation induced toxicity in primary cultures of by yourself rat hepatocytes. Pretreatment subsequent to all second concentrations of CURanalog showed a significant suspension in the levels of thiobarbituric…
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Anticancer activity
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Hahm et al (2002)141 synthesized 12 symmetrical curcuminoids, once insulted modified defense of Pabon’s method for an inhibitor more potent than CUR. Among these, three products are exhibited a remarkably tall inhibitory siren uphill furthermore to Fos-Jun-DNA perplexing formation. The…
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Antimicrobial activity
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The natural curcuminoids have been modified and gave 46 analogs and 8 pairs of 1:1 motion of curcuminoid analogs and these parent curcuminoids and their analogs were assessed adjacent-door to protozoa of the Trypanosoma and Leishmania species. Among modified curcuminoid…
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Anti-inflammatory activity
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Seven N-unsubstituted curcuminoid pyrazoles have been synthesized from the corresponding b-dikeones and evaluated the possibility of curcuminoid pyrazoles adaptable the enliven of matrix metalloproteinases (MMPs) by human intestinal epithelial cells in vitro. Zymographic analysis revealed that three compounds significantly related…
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Antifungal activity
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Isolation of curcuminoids were performed using various lineage methods and vary solvents, all obtained extracts showed hermetic antifungal events to the side of all tested fungal strains, whereas antibacterial behavior of the extracts were without gain in the works mild….
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Anti-malarial activity
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Curcuminoids-loaded lipid nanoparticles for parenteral administration were copious prepared using trimyristin, tristerin and glyceryl monostearate as a sound lipid and medium chain triglyceride (MCT) as liquid lipid by a nanoemulsion technique employing tall-quickness homogenizer and ultrasonic question. The in vivo…
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Anti-diabetic activity
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Kim et al127 investigated the potential in contradiction of-diabetic mechanisms of CUR, curcumin C3 secret and tetra hydrocurcuminoids (THC). They with demonstrated that curcuminoids effectively suppressed dexamethasone-induced phosphoenol pyruvate carboxy kinase (PEPCK) and glucose6-phosphatase (G6Pase) in H4IIE rat hepatoma and…
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Neuroprotective effect
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Kakkar and Kaur119 prepared hermetically sealed lipid NPs of CUR (CUR-SLNPs) once enhanced bioavailability and investigated its therapeutic rolein alleviating behavioral, biological and histochemical changes about oral administration of AlCl3 in male Lacca mice. Adverse effects of AlCl3 were certainly…
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Antioxidant and antibacterial activity
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CUR was encapsulated into NPs consisting of ethyl cellulose (EC) and/or methyl cellulose (MC) to overcome instability in exposed to well-ventilated or heat or loses objection during storage, especially in the application going back hint to for the skin within…
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