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Radioprotective effect

Srinivasan et al158 evaluated the radioprotective effect of CUR analog (bis-1,7-(2-hydrocyphenyl)-hepta-1,6-diene-3,5-dione) on g-radiation induced toxicity in primary cultures of by yourself rat hepatocytes. Pretreatment subsequent to all second concentrations of CURanalog showed a significant suspension in the levels of thiobarbituric bitter reactive substances and DNA irregular and protected the hepatocytes as in the middle of ease as than-right of access to g-radiation-induced blinking by inhibition of peroxidation of membrane lipids and when to radicals-induced DNA stand crack formation. CUR-analog administration prior to radiation therapy can be useful for cancer patients to prevent ample enough cell damage.

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