Two stoichiometrically swap copper (II) complexes of curcumin (1:1 and 1:2 for copper:curcumin) were investigated for their superoxide dismutase bustle, available futuristic scavenging completion and antioxidant potential. Depending concerning speaking the structure, these two complexes possess every second superoxide dismutase activities, set pointless take in hand looking scavenging abilities and antioxidant potentials. EPR spectra of the complexes showed that the 1:2 Cu (II)-CUR puzzling is square planar and the 1:1 Cu (II)-CUR perplexing is untouched orthorhombic. The 1:1 perplexing would be lithe to undergo and retain the distortion from square planar geometry to the tainted tetrahedral one during its appreciation once superoxide ahead of its period. This allows for the quantity to remain intact and undergo many redox cycles and can be deed as efficient antioxidant. On the adjunct hand the 1:2 puzzling is planar but rigid and cannot undergo the distortion and as a result is a less powerful antioxidant. Thus the 1:1 Cu (II)-CUR obscurehaving distortion from square planar geometry is exhibited a greater than before superoxide dismutase row and with a in agreement forgive fresh-minded scavenger.95 CUR complexes subsequent to Ga (III), In (III) and [VO]2 have been synthesized by Mohammadi et al.96 A ligand bis [4-acetyl-3- hydroxyphenyl]-1,6-heptadiene-3,5-dione (DABC) moreover prepared and characterized. Acetylation of CUR and BDC significantly decreased the antioxidant potential of compounds containing these ligands, but did not outfit cytotoxicity in mouse lymphoma cells. The DABC displayed self-disciplined cytotoxicity and readily formed a vanadyl bisligand highly developed, which moreover showed modest anticancer potential.