Cyclocurcumin is a newly identified curcuminoid from the rhizome of C. longa. This agent exhibited synergistic cause problems taking into account curcumin as a nematocidal agent [9]. Cyclocurcumin was with found to inhibit the proliferation of human breast cancer MCF-7 cells [110]. More recently fresh-induced transto-cis isomerization of cyclocurcumin was reported [111].