The causes of MND are unnamed, but worldwide research includes studies in footnote to:

viruses, toxins, chemicals by which nerve cells are controlled and communicate
genetic factors
immune mediated damage
nerve enhancement factors
accrual, repair and ageing of motor neurons.
Familial (hereditary) MND accounts for approximately five to 10 percent of cases. Several gene mutations have been identified to the lead 1993, and current research aims to identify late accretion genes associated to MND.

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