Calebin A is a novel curcuminoid and no-one else from C. longa. Like curcumin, this complex can inhibit cell cassette and induce apoptosis in drug-resistant human gastric cancer cells [112]. How calebin mediates its effects is not sure, but authors have shown that the drug efflux undertaking of P-glycoprotein was inhibited without affecting its freshening. This agent shortened S phase and G2/M phase arrest in cells and modulated the actions of JNK, ERK, and p38 MAPK. Thus, calebin A exhibits bustle in opposition to human gastric and perhaps toting happening cancers. Like curcumin, calebin A has with been shown to guard neuronal cells from -amyloid ill-treatment [113].